DePuy Manufacturing was founded in 1895 in Warsaw, Indiana by Revra DePuy. The company originally manufactured and sold fiber splints used to immobilize limbs while fractured bones healed.
DePuy was acquired by Johnson & Johnson in 1998 as part of the company's Medical Devices & Diagnostics Group. It presently operates in many countries, either under the DePuy name or as a brand under the Johnson & Johnson organization.
Among other medical products, DePuy manufactures and markets various devices used in reconstructing damaged or diseased joints and reconstructing other skeletal injuries. These included the ASR™ Hip Resurfacing System and the ASR™ XL Acetabular System, until production ceased in 2009.